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DYNE-251

Duchenne Muscular Dystrophy (DMD) amenable to exon 51 skipping

Phase 1/2ActiveNCT05524883

Key Facts

Indication
Duchenne Muscular Dystrophy (DMD) amenable to exon 51 skipping
Phase
Phase 1/2
Status
Active
Company

About Dyne Therapeutics

Dyne Therapeutics is focused on developing life-transforming therapies for patients with genetically driven muscle diseases through its proprietary FORCE™ (Fragment, Oligonucleotide, Conjugate) platform. This platform enables the targeted delivery of therapeutic payloads to muscle tissue, addressing the root cause of diseases with high unmet need. The company has rapidly advanced multiple candidates into clinical development, with promising early data demonstrating target engagement and biomarker correction. Dyne's strategic approach combines validated oligonucleotide modalities with tissue-specific targeting to overcome historical delivery challenges in muscle disorders.

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