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Diagnostic Imaging Agents

Acidic Tissue Diseases

Phase 1Active

Key Facts

Indication
Acidic Tissue Diseases
Phase
Phase 1
Status
Active
Company

About pHLIP

pHLIP, Inc. is a private, clinical-stage biotech leveraging its unique pH-sensitive peptide platform to enable precise targeting of acidic microenvironments found in solid tumors, inflamed, and fibrotic tissues. Its core technology allows for the selective delivery of payloads—ranging from small molecules and proteins to nanoparticles—either to the cell surface or directly into the cytoplasm, aiming to enhance efficacy and reduce systemic side effects. The company has demonstrated proof-of-concept for tumor targeting in humans and is advancing a pipeline focused on oncology and inflammatory diseases. With its platform-agnostic approach, pHLIP seeks to create novel targeted therapies and improve existing treatment modalities.

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