Diadem for Chronic Pain

About Spire Therapeutics

Spire Therapeutics is pioneering a novel, non-invasive neuromodulation platform using transcranial focused ultrasound (tFUS) to treat severe neurological conditions. Its lead device, Diadem, is designed to overcome key technical barriers like skull and hair distortion to deliver precise, controlled therapy to deep brain targets. The company is currently conducting Phase 3 clinical trials for chronic pain and depression, supported by prestigious grants and private investment, positioning it to address a large unmet need in treatment-resistant patient populations.

Therapeutic Areas