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Deucrictibant

Prophylactic & On-demand treatment of Acquired Angioedema due to C1-INH deficiency (AAE-C1INH)

Phase 3Active (CREAATE trial)

Key Facts

Indication
Prophylactic & On-demand treatment of Acquired Angioedema due to C1-INH deficiency (AAE-C1INH)
Phase
Phase 3
Status
Active (CREAATE trial)
Company

About Pharvaris

Pharvaris is a clinical-stage biotech focused on transforming the treatment landscape for hereditary angioedema (HAE) and other bradykinin-mediated conditions by developing oral alternatives to current injectable therapies. The company's lead asset, deucrictibant, is a potent, oral small-molecule B2 receptor antagonist being evaluated in two pivotal Phase 3 trials (RAPIDe-3 for on-demand and CHAPTER-3 for prophylaxis) and has shown promising efficacy and safety in Phase 2 studies. With a seasoned leadership team and a clear mission to provide patient choice through convenient, effective oral treatments, Pharvaris is positioned to address significant unmet needs in the rare disease market.

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