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CT1812

Mild-to-Moderate Alzheimer's Disease

Phase 2Active, EnrollingNCT05531656

Key Facts

Indication
Mild-to-Moderate Alzheimer's Disease
Phase
Phase 2
Status
Active, Enrolling
Company

About Cognition Therapeutics

Cognition Therapeutics is a neuroscience-focused biotech developing small molecule modulators of the sigma-2 receptor complex to halt synaptic damage in neurodegenerative diseases. Its lead asset, CT1812, has generated encouraging biomarker and cognitive signal in multiple Phase 2 studies in Alzheimer's disease and is also being evaluated in dementia with Lewy bodies. The company's strategy leverages a differentiated mechanism of action, supported by non-dilutive grant funding, to advance its pipeline toward pivotal trials in substantial markets with high unmet need. As a micro-cap public company, its near-term value inflection is tied to the clinical readouts from its ongoing SHINE and SHIMMER trials.

View full company profile

About Cognition Therapeutics

Cognition Therapeutics is a neuroscience-focused biotech developing small molecule modulators of the sigma-2 receptor complex to halt synaptic damage in neurodegenerative diseases. Its lead asset, CT1812, has generated encouraging biomarker and cognitive signal in multiple Phase 2 studies in Alzheimer's disease and is also being evaluated in dementia with Lewy bodies. The company's strategy leverages a differentiated mechanism of action, supported by non-dilutive grant funding, to advance its pipeline toward pivotal trials in substantial markets with high unmet need. As a micro-cap public company, its near-term value inflection is tied to the clinical readouts from its ongoing SHINE and SHIMMER trials.

View full company profile

About Cognition Therapeutics

Cognition Therapeutics is a neuroscience-focused biotech developing small molecule modulators of the sigma-2 receptor complex to halt synaptic damage in neurodegenerative diseases. Its lead asset, CT1812, has generated encouraging biomarker and cognitive signal in multiple Phase 2 studies in Alzheimer's disease and is also being evaluated in dementia with Lewy bodies. The company's strategy leverages a differentiated mechanism of action, supported by non-dilutive grant funding, to advance its pipeline toward pivotal trials in substantial markets with high unmet need. As a micro-cap public company, its near-term value inflection is tied to the clinical readouts from its ongoing SHINE and SHIMMER trials.

View full company profile

About Cognition Therapeutics

Cognition Therapeutics is a neuroscience-focused biotech developing small molecule modulators of the sigma-2 receptor complex to halt synaptic damage in neurodegenerative diseases. Its lead asset, CT1812, has generated encouraging biomarker and cognitive signal in multiple Phase 2 studies in Alzheimer's disease and is also being evaluated in dementia with Lewy bodies. The company's strategy leverages a differentiated mechanism of action, supported by non-dilutive grant funding, to advance its pipeline toward pivotal trials in substantial markets with high unmet need. As a micro-cap public company, its near-term value inflection is tied to the clinical readouts from its ongoing SHINE and SHIMMER trials.

View full company profile

Other Mild-to-Moderate Alzheimer's Disease Drugs

DrugCompanyPhase
ALPHA-1062Alpha CognitionPhase 2