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CRB-701

Nectin-4 expressing solid tumors (e.g., Cervical Cancer, HNSCC, mUC)

Phase 1Active

Key Facts

Indication
Nectin-4 expressing solid tumors (e.g., Cervical Cancer, HNSCC, mUC)
Phase
Phase 1
Status
Active
Company

About Corbus Pharmaceuticals

Corbus Pharmaceuticals is a clinical-stage biotech focused on developing innovative treatments for cancer and obesity, two of the most pressing global health challenges. Its strategy centers on optimizing known therapeutic modalities: a next-generation Nectin-4-targeting ADC (CRB-701) designed to improve upon first-generation toxicity, and a peripherally-restricted CB1 inverse agonist (CRB-913) aimed at achieving weight loss without central nervous system side effects. The company has advanced both lead assets into Phase 1 clinical trials, secured Fast Track designation for CRB-701 in specific cancers, and is positioning itself in multi-billion dollar markets with high unmet need.

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Therapeutic Areas