Home/Pipeline/CPI-613 (devimistat) + Cytarabine/Mitoxantrone

CPI-613 (devimistat) + Cytarabine/Mitoxantrone

Relapsed or Refractory Acute Myeloid Leukemia (AML)

Phase 3Active, not recruitingNCT03504410

Key Facts

Indication
Relapsed or Refractory Acute Myeloid Leukemia (AML)
Phase
Phase 3
Status
Active, not recruiting
Company

About Rafael Holdings

Rafael Holdings is a clinical-stage biotech focused on developing novel oncology and rare disease therapeutics. Its core mission is to improve and extend the lives of patients with difficult-to-treat diseases by targeting cancer metabolism and lysosomal function. The company's strategy leverages its lead asset, devimistat, in late-stage trials for solid tumors and hematologic malignancies, while integrating new platforms through strategic mergers. With two Phase 3 trials ongoing and a recent expansion into rare diseases, Rafael is transitioning from a clinical-stage entity toward a potential commercial enterprise.

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Other Relapsed or Refractory Acute Myeloid Leukemia (AML) Drugs

DrugCompanyPhase
Fosciclopirox (Ciclopirox Prodrug)CicloMedPhase 1B/2A
Annamycin (AnnAraC)Moleculin BiotechPhase 3