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CLB-4000 + Peg-IFNα-2a

Chronic Hepatitis B Infection (CHB)

Phase 1bPlanned (within ongoing study)ACTRN12625000250437, ACTRN12625000204448

Key Facts

Indication
Chronic Hepatitis B Infection (CHB)
Phase
Phase 1b
Status
Planned (within ongoing study)
Company

About ClearB Therapeutics

ClearB Therapeutics is focused on addressing the substantial unmet need in chronic hepatitis B by developing immune-redirecting therapeutic vaccines. Its lead candidate, CLB-4000, is a bivalent subunit vaccine comprised of engineered HBsAg variants designed to over-represent clearance profile epitopes, adjuvanted with a novel saponin. The company has initiated a Phase 1b clinical trial in non-cirrhotic adults with CHB and is positioned to contribute to evolving treatment regimens aimed at functional cure.

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Other Chronic Hepatitis B Infection (CHB) Drugs

DrugCompanyPhase
CLB-4000ClearB TherapeuticsPhase 1b