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Cardiac Assist Device

Heart Failure

Pre-clinicalActive

Key Facts

Indication

Heart Failure

Phase

Pre-clinical

Status

Active

Company

Second Heart Assist

About Second Heart Assist

Second Heart Assist is an early-stage medical device innovator targeting the large and growing heart failure market. The company is developing a minimally invasive cardiac assist device, positioning itself as a potential disruptor in the mechanical circulatory support (MCS) space by aiming to reduce procedural complexity and patient trauma compared to existing ventricular assist devices (VADs). As a private, pre-revenue company, its success hinges on securing development funding, achieving key clinical and regulatory milestones, and ultimately demonstrating superior safety and efficacy to capture market share from established players.

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Therapeutic Areas

Cardiovascular Heart Failure

Other Heart Failure Drugs

Drug	Company	Phase	Status
Cardiac Cell Therapy Program	StemCardia	Pre-clinical	Active
NTP42	ATXA Therapeutics	Preclinical	Platform potential identified
Heart Failure Trial	Clinical Investigation Specialists	Not Specified	Actively Recruiting
INPEFA (sotagliflozin)	Lexicon Pharmaceuticals	Approved	Commercial
MyCardia™	Avery Therapeutics	Pre-clinical	Active
Isosorbide Dinitrate/Hydralazine HCl Tablets	i3 Pharmaceuticals	Approved	Active
TLT-101	TikkunLev Therapeutics	Pre-clinical	Active
Undisclosed Heart Regeneration Program	Animatus Biosciences	Pre-clinical	Active
AFteR Registry	Occlutech	N/A (Registry)	Active
biotx.ai Target Discovery Collaboration	HeartBeat.bio	Pre-clinical	Active
Surlorian	RyCarma Therapeutics	Phase 2	Active
Coronary Sinus Reduction	Shockwave Medical	Unknown	Active