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ANX007

Geographic Atrophy (GA)

Phase 2Active - Phase 3-ready

Key Facts

Indication
Geographic Atrophy (GA)
Phase
Phase 2
Status
Active - Phase 3-ready
Companies

About Annexon Biosciences

Annexon Biosciences is developing first-in-class C1q inhibitors to halt the classical complement pathway, a key driver of tissue damage in severe diseases of the body, brain, and eye. Founded on groundbreaking research from Stanford, the company has built a versatile platform with multiple drug candidates in late-stage clinical trials, including ANX005 for GBS and ANX007 for geographic atrophy. Its strategy focuses on achieving functional clinical benefits in areas of high unmet need, positioning it as a leader in upstream complement inhibition with significant near-term catalysts.

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About Annexon Biosciences

Annexon Biosciences is developing first-in-class C1q inhibitors to halt the classical complement pathway, a key driver of tissue damage in severe diseases of the body, brain, and eye. Founded on groundbreaking research from Stanford, the company has built a versatile platform with multiple drug candidates in late-stage clinical trials, including ANX005 for GBS and ANX007 for geographic atrophy. Its strategy focuses on achieving functional clinical benefits in areas of high unmet need, positioning it as a leader in upstream complement inhibition with significant near-term catalysts.

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About Annexon

Annexon is a leader in developing C1q-targeting monoclonal antibodies to inhibit the classical complement pathway, a key driver of inflammation and neurodegeneration. Founded on seminal research from Stanford neurobiology, the company has built a late-stage pipeline with lead programs in Guillain-Barré Syndrome (GBS) and Geographic Atrophy (GA). Its strategy focuses on achieving functional benefits for patients by blocking complement activation upstream, potentially offering a more comprehensive and selective therapeutic profile than downstream inhibitors.

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About Annexon

Annexon is a leader in developing C1q-targeting monoclonal antibodies to inhibit the classical complement pathway, a key driver of inflammation and neurodegeneration. Founded on seminal research from Stanford neurobiology, the company has built a late-stage pipeline with lead programs in Guillain-Barré Syndrome (GBS) and Geographic Atrophy (GA). Its strategy focuses on achieving functional benefits for patients by blocking complement activation upstream, potentially offering a more comprehensive and selective therapeutic profile than downstream inhibitors.

View full company profile

Other Geographic Atrophy (GA) Drugs

DrugCompanyPhase
NGM621NGM BiopharmaceuticalsPhase 2
K8 ImplantInflammasome TherapeuticsPhase I/II
IONIS-FB-LRxIonis PharmaceuticalsPhase 3