Home/Pipeline/ALX-001

ALX-001

Alzheimer's Disease

Phase 1bActive

Key Facts

Indication
Alzheimer's Disease
Phase
Phase 1b
Status
Active
Company

About Allyx Therapeutics

Allyx Therapeutics is a private, Series A-stage biotech based in New Haven, CT, pioneering a synapse-protection approach for neurodegenerative diseases. Its lead asset, ALX-001, is a first-in-class, oral mGluR5 modulator that has completed Phase 1a/b studies, demonstrating safety, full brain receptor occupancy, and progression into patient trials for both Alzheimer's and Parkinson's disease. The company is backed by venture capital and significant non-dilutive NIH funding, positioning it to advance into Phase 2 clinical development.

View full company profile

About Allyx Therapeutics

Allyx Therapeutics is a private, Series A-stage biotech based in New Haven, CT, pioneering a synapse-protection approach for neurodegenerative diseases. Its lead asset, ALX-001, is a first-in-class, oral mGluR5 modulator that has completed Phase 1a/b studies, demonstrating safety, full brain receptor occupancy, and progression into patient trials for both Alzheimer's and Parkinson's disease. The company is backed by venture capital and significant non-dilutive NIH funding, positioning it to advance into Phase 2 clinical development.

View full company profile

Other Alzheimer's Disease Drugs

DrugCompanyPhase
NUZ-001Neurizon TherapeuticsPreclinical
ALZN002Alzamend NeuroPreclinical
P021Phanes BiotechPreclinical
PB43DPhanes BiotechPreclinical
UB-311VaxxinityPhase 2
LecanemabBioArcticLaunched
BAN2401BioArcticPreclinical
Undisclosed Programsjohnson-and-johnson-innovative-medicinePipeline
MK-6240 (florquinitau)Lantheus Medical ImagingRegulatory Filing
NAV-4694 (flutafuranol)Lantheus Medical ImagingPhase 3
LNTH-2620/PI-2620Lantheus Medical ImagingPhase 3
itMSCsStemedica Cell TechnologiesClinical Development