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AL101 / GSK4527226

Early Alzheimer's Disease

Phase 2Active - PROGRESS-AD trial

Key Facts

Indication
Early Alzheimer's Disease
Phase
Phase 2
Status
Active - PROGRESS-AD trial
Company

About Alector

Founded in 2013 and publicly traded on Nasdaq, Alector is on a mission to slow and prevent neurodegenerative diseases by harnessing insights from human genetics, immunology, and neuroscience. The company has built a robust pipeline of potential first- and best-in-class candidates, with its lead program, latozinemab (AL001), in a pivotal Phase 3 trial for frontotemporal dementia and AL101 in Phase 2 for Alzheimer's disease via a major collaboration with GSK. Alector's strategy combines internal R&D with high-value partnerships, supported by a seasoned leadership team with deep expertise in drug discovery and development.

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Other Early Alzheimer's Disease Drugs

DrugCompanyPhase
Lecanemab (Leqembi®)BioArctic ABApproved
AL002AlectorPhase 2
Sabirnetug (ACU193) - Intravenous (IV)Acumen PharmaceuticalsPhase 2
Sabirnetug (ACU193) - Subcutaneous (SC)Acumen PharmaceuticalsPhase 1
Enhanced Brain Delivery (EBD™) [TfR-Brain transporter + AβO mAb]Acumen PharmaceuticalsPreclinical