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AGLE-102

Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Phase 1/2Active

Key Facts

Indication
Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Phase
Phase 1/2
Status
Active
Company

About Aegle Therapeutics

Aegle Therapeutics is a private, clinical-stage biotech founded in 2015 and based in Miami, Florida, operating in the biologics sector. The company is developing a novel therapeutic platform based on extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs), with its lead program AGLE-102 in a Phase 1/2 trial for Recessive Dystrophic Epidermolysis Bullosa (RDEB). Aegle's technology aims to leverage the inherent signaling and cargo-delivery functions of EVs to treat rare diseases with high unmet need, positioning it at the forefront of the emerging EV therapeutics field. The company is currently pre-revenue and focused on advancing its clinical pipeline.

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Other Recessive Dystrophic Epidermolysis Bullosa (RDEB) Drugs

DrugCompanyPhase
ABCB5+ MSCs (systemic)RHEACELLPhase III