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4D-150

Wet Age-Related Macular Degeneration (wet AMD)

Phase 3Active - SPECTRA trial enrolling

Key Facts

Indication
Wet Age-Related Macular Degeneration (wet AMD)
Phase
Phase 3
Status
Active - SPECTRA trial enrolling
Company

About 4D Molecular Therapeutics

4D Molecular Therapeutics is a visionary gene therapy company leveraging its proprietary Therapeutic Vector Evolution platform to design customized adeno-associated viral (AAV) vectors for specific diseases. The company's most advanced assets target retinal conditions, with 4D-150 showing promising Phase 2 data in wet age-related macular degeneration (AMD) and diabetic macular edema (DME), significantly reducing the need for frequent anti-VEGF injections. With a strategic focus on retina and pulmonology, bolstered by significant partnerships and non-dilutive funding, 4DMT is positioned to advance multiple programs into late-stage development and potentially bring transformative one-time treatments to patients.

View full company profile

About 4D Molecular Therapeutics

4D Molecular Therapeutics is a visionary gene therapy company leveraging its proprietary Therapeutic Vector Evolution platform to design customized adeno-associated viral (AAV) vectors for specific diseases. The company's most advanced assets target retinal conditions, with 4D-150 showing promising Phase 2 data in wet age-related macular degeneration (AMD) and diabetic macular edema (DME), significantly reducing the need for frequent anti-VEGF injections. With a strategic focus on retina and pulmonology, bolstered by significant partnerships and non-dilutive funding, 4DMT is positioned to advance multiple programs into late-stage development and potentially bring transformative one-time treatments to patients.

View full company profile

Other Wet Age-Related Macular Degeneration (wet AMD) Drugs

DrugCompanyPhase
OTX-TKI (axitinib implant)Ocular TherapeutixPhase 3
DURAVYU™ (EYP-1901)EyePoint PharmaceuticalsPhase 3
Sozinibercept (OPT-302)OptheaPhase 3
ONS-5010 / LYTENAVA™ (bevacizumab-vikg)Outlook TherapeuticsApproved