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4D-150

Wet Age-Related Macular Degeneration

Phase 3Active

Key Facts

Indication
Wet Age-Related Macular Degeneration
Phase
Phase 3
Status
Active
Company

About 4D Molecular Therapeutics

4D Molecular Therapeutics is a platform-driven gene therapy company leveraging its proprietary Therapeutic Vector Evolution (TVE) platform to engineer optimized AAV vectors for specific diseases. The company has advanced two lead programs into Phase 3 for wet age-related macular degeneration (AMD) and diabetic macular edema (DME), demonstrating significant reductions in treatment burden, and has a Phase 1/2 program in cystic fibrosis. Its strategy focuses on large markets with high unmet need, validated by strategic partnerships with Astellas and Otsuka, and funding from the Cystic Fibrosis Foundation.

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About 4D Molecular Therapeutics

4D Molecular Therapeutics is a platform-driven gene therapy company leveraging its proprietary Therapeutic Vector Evolution (TVE) platform to engineer optimized AAV vectors for specific diseases. The company has advanced two lead programs into Phase 3 for wet age-related macular degeneration (AMD) and diabetic macular edema (DME), demonstrating significant reductions in treatment burden, and has a Phase 1/2 program in cystic fibrosis. Its strategy focuses on large markets with high unmet need, validated by strategic partnerships with Astellas and Otsuka, and funding from the Cystic Fibrosis Foundation.

View full company profile

Therapeutic Areas

Other Wet Age-Related Macular Degeneration Drugs

DrugCompanyPhase
Wet AMD ProgramExonatePre-clinical
AKST4290AlkahestPhase 2
AXPAXLI (OTX-TKI)Ocular TherapeutixNDA Submitted