Xona Microfluidics

Xona Microfluidics is a specialized tools and services company at the intersection of microengineering and neuroscience. It commercializes the seminal 'XonaChip' platform, which enables the precise compartmentalization of neuronal cultures for studying subcellular processes, axon biology, and disease models. Beyond product sales, the company has leveraged its scientific expertise to build a contract research organization (CRO) arm and consistently secures NIH grant funding for R&D. Positioned in the Research Triangle Park ecosystem, Xona serves academic, biotech, and pharmaceutical researchers aiming to de-risk neurological drug discovery.

Compartmentalized microfluidic devices (XonaChips) for culturing neurons, enabling fluidic and physical separation of neuronal cell bodies from axons and synapses. Platforms are available in PDMS and cyclic olefin copolymer (COC), supporting long-term culture of primary and iPSC-derived neurons for modeling disease, injury, and synaptic function.

Xona competes in the niche market of specialized neuronal culture systems. Competitors include other microfluidic companies (e.g., Emulate, Cherry Biotech) with neuron-focused chips, as well as traditional cell culture insert providers. Xona's key differentiator is its exclusive license to the foundational technology, deep neuroscience expertise, and its validated track record in over 1,000 publications.