Xenetic Biosciences

Xenetic Biosciences

XBIOPhase 2

Xenetic Biosciences is a publicly-traded biopharma company developing adjunctive cancer therapies based on its DNase I platform, which targets neutrophil extracellular traps (NETs) to overcome resistance to standard treatments. The company is strategically positioned in the high-value oncology space, with a focus on pancreatic cancer and other solid tumors, and is backed by a team with significant industry experience. Its strategy involves advancing its lead candidate into clinical trials while leveraging key partnerships with research institutions and manufacturing organizations.

Market Cap
$7.5M
Focus
BiologicsVaccines

XBIO · Stock Price

USD 3.267.39 (-69.39%)

Historical price data

AI Company Overview

Xenetic Biosciences is a publicly-traded biopharma company developing adjunctive cancer therapies based on its DNase I platform, which targets neutrophil extracellular traps (NETs) to overcome resistance to standard treatments. The company is strategically positioned in the high-value oncology space, with a focus on pancreatic cancer and other solid tumors, and is backed by a team with significant industry experience. Its strategy involves advancing its lead candidate into clinical trials while leveraging key partnerships with research institutions and manufacturing organizations.

Technology Platform

DNase I platform designed to degrade neutrophil extracellular traps (NETs) to overcome cancer treatment resistance and inhibit metastasis, intended for use as an adjunctive therapy with existing immunotherapies and chemotherapies.

Pipeline Snapshot

1

1 drug in pipeline

DrugIndicationStageWatch
Sodium Cridanimod + progestin therapyEndometrial CancerPhase 2

Funding History

2

Total raised: $15M

PIPE$10MUndisclosedDec 15, 2021
PIPE$5MUndisclosedSep 15, 2020

Opportunities

The primary opportunity is establishing DNase I as a new standard adjunctive therapy for pancreatic cancer and other solid tumors, addressing a massive unmet need.
Success could lead to partnerships or acquisition by a larger pharma company.
The platform's modular nature allows for expansion into combination therapies with various existing treatments.

Risk Factors

Key risks include the high failure rate of novel drug mechanisms, dependence on future capital raises to fund clinical trials, and potential competition from other companies targeting NETs or the tumor microenvironment.
Execution risk is heightened due to reliance on a lean team and external partners.

Competitive Landscape

Xenetic is an early mover in the emerging field of NETs-targeting cancer therapies. Direct competition comes from a handful of private biotechs, while indirect competition includes all companies developing therapies to modulate the tumor microenvironment. Differentiation lies in its systemic enzyme approach and strategy to enhance existing treatments rather than replace them.

Company Info

TypeTherapeutics
LocationUnited States
StagePhase 2
RevenuePre-revenue

Trading

TickerXBIO
ExchangeNASDAQ

Therapeutic Areas

OncologyImmuno-Oncology

Partners

VolitionTakeda Pharmaceutical Co. Ltd.CLS Therapeutics Ltd.Catalent Pharma Solutions LLCScripps Research
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