Vanda Pharmaceuticals

Vanda Pharmaceuticals

VNDA
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VNDA · Stock Price

USD 6.39+2.44 (+61.77%)
Market Cap: $384.3M

Historical price data

Market Cap: $384.3MPipeline: 77 drugs (31 Phase 3)Patents: 20Founded: 2003HQ: Washington DC, United States

Overview

Vanda Pharmaceuticals is a publicly traded biopharma company with a mission to 'innovate in the service of people's pursuit of happiness' by developing targeted therapies for CNS and sleep disorders. Its core strategy integrates genetics and genomics into all stages of drug development to enhance clinical trial success and commercial positioning. Key achievements include the FDA approvals of Fanapt® for schizophrenia and Hetlioz® for Non-24, with recent milestones including the 2026 approval of BYSANTI™ and a landmark FDA hearing for Hetlioz® in Jet Lag Disorder.

NeuropsychiatrySleep-Wake DisordersDermatologyOncology

Technology Platform

Integrated genetics and pharmacogenetics platform applied to drug development for patient stratification, optimized clinical trials, and precision commercialization.

Pipeline

77
77 drugs in pipeline31 in Phase 3
DrugIndicationStageWatch
tasimelteon 20 mg capsule + tasimelteon 2 mg I.V.Non-24-Hour-Sleep-Wake DisorderApproved
IloperidoneSchizophreniaApproved
ImsidolimabGeneralized Pustular PsoriasisPhase 3
Iloperidone + PlaceboSchizophreniaPhase 3
Iloperidone + Ziprasidone + PlaceboSchizophreniaPhase 3

Funding History

3
Total raised:$80M
IPO$50M
Series B$20M
Series A$10M

FDA Approved Drugs

4
PONVORYNDAMar 18, 2021
HETLIOZ LQNDADec 1, 2020
HETLIOZNDAJan 31, 2014

Opportunities

Near-term catalysts include FDA decisions on Hetlioz® for Jet Lag Disorder and Smith-Magenis Syndrome, which could significantly expand its market.
The recent approval and launch of BYSANTI™ and the BLA filing for imsidolimab in GPP represent diversification into new mechanisms and therapeutic areas with substantial addressable markets.

Risk Factors

Key risks include clinical/regulatory setbacks for late-stage pipeline candidates, intense competition and commercial execution challenges in psychiatry, financial constraints typical of a micro-cap biotech, and reliance on a limited number of commercial products for revenue.

Competitive Landscape

Vanda competes in niche, high-unmet-need markets (e.g., Non-24) with limited direct competition but faces giants in crowded CNS spaces like schizophrenia. Its differentiation relies on pharmacogenetic targeting and novel mechanisms, but commercial scale is a challenge against larger, well-resourced competitors.

Company Timeline

2003Founded

Founded in Washington DC, United States

2003Series A

Series A: $10.0M

2004Series B

Series B: $20.0M

2006IPO

IPO — $50.0M

2014FDA Approval

FDA Approval: HETLIOZ

2020FDA Approval

FDA Approval: HETLIOZ LQ