Twist Bioscience

Twist Bioscience

TWST
South San Francisco, United States· Est. 2013

Twist Bioscience leverages its proprietary silicon-based DNA synthesis platform to manufacture high-quality, precise synthetic DNA at scale, enabling innovation across diverse fields. The company has expanded from core gene synthesis into high-growth markets like next-generation sequencing (NGS), antibody discovery, and synthetic biology tools. As a publicly traded company, Twist aims to be the foundational platform for the bioeconomy, supporting customers in accelerating research and development timelines.

TWST · Stock Price

USD 47.49+5.61 (+13.40%)
Market Cap: $3.1B

Historical price data

AI Company Overview

Twist Bioscience leverages its proprietary silicon-based DNA synthesis platform to manufacture high-quality, precise synthetic DNA at scale, enabling innovation across diverse fields. The company has expanded from core gene synthesis into high-growth markets like next-generation sequencing (NGS), antibody discovery, and synthetic biology tools. As a publicly traded company, Twist aims to be the foundational platform for the bioeconomy, supporting customers in accelerating research and development timelines.

OncologyInfectious DiseaseImmunologyGenetic Diseases

Technology Platform

Proprietary silicon-based DNA synthesis platform that enables high-throughput, precise, and cost-effective manufacturing of synthetic DNA, serving as the foundation for genes, oligo pools, NGS solutions, and synthetic biology tools.

Pipeline

1
1 drug in pipeline
DrugIndicationStageWatch
Human mAb 216 + VincristineLeukemia, Lymphocytic, AcutePhase 1

Funding History

4
Total raised:$178M
IPO$70MOct 30, 2018
Series C$61MDec 15, 2016
Series B$37MOct 15, 2015
Series A$10MJan 15, 2014

Opportunities

Significant growth opportunities exist in penetrating the large NGS target enrichment market, scaling the high-margin antibody discovery services with more biopharma partners, and expanding the use of synthetic controls for regulatory-grade diagnostic development.
The long-term opportunity in DNA data storage represents a potential paradigm-shifting market.

Risk Factors

Key risks include intense competition across all product segments, execution challenges in scaling a multi-product commercial organization, the cyclical nature of biopharma R&D spending, and the need to demonstrate a clear path to sustained profitability and positive cash flow.

Competitive Landscape

Twist competes with established players like IDT and GenScript in gene synthesis, Agilent and Roche in NGS capture, and specialized CROs in antibody discovery. Its core differentiation is its cost-effective, high-throughput silicon-based DNA synthesis platform, which provides scalability and quality advantages that are difficult for competitors to replicate.