System Biosciences

System Biosciences

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Private Company

Total funding raised: $43M

Overview

System Biosciences is a private, revenue-generating biotechnology tools and services company that has established itself as a significant player in the research reagents market. Its business model centers on providing a broad portfolio of platform technologies, including exosome isolation and analysis kits, viral and non-viral gene delivery systems, CRISPR tools, and custom services like lentivirus packaging and stable cell line generation. While not a therapeutic developer itself, SBI's products are critical enablers for discovery-stage research across genetics, genomics, gene therapy, and biomarker discovery, positioning it to benefit from the growth of these fields. The company leverages its scientific expertise to commercialize novel research tools, aiming to be first-to-market with new inventions.

Genetics & GenomicsGene TherapyCRISPR

Technology Platform

Portfolio of research tools and services spanning exosome isolation/analysis, viral/non-viral gene delivery systems (lentivirus, AAV, minicircles), CRISPR/Cas9 genome editing, imaging/reporter vectors, and liquid biopsy.

Funding History

2
Total raised:$43M
Series B$28M
Series A$15M

Opportunities

SBI is positioned to capitalize on the explosive growth in exosome research for biomarkers and therapeutics, the sustained demand for gene delivery and editing tools from the gene therapy boom, and the expanding market for outsourced research services.
Its multi-platform approach allows it to serve as a one-stop shop for discovery-phase research.

Risk Factors

Key risks include intense competition in the research tools market, dependency on cyclical research funding from grants, the rapid pace of technological obsolescence requiring constant innovation, and navigating complex intellectual property landscapes in areas like CRISPR.

Competitive Landscape

SBI competes in the fragmented life science research tools market against large conglomerates like Thermo Fisher Scientific and Merck KGaA, specialized public companies like Takara Bio, and numerous private startups. Its differentiation lies in its focused expertise in exosomes and gene delivery, a broad integrated portfolio, and a service-oriented, scientifically-driven customer approach.