Synthego

Synthego

Is this your company? Claim your profile to update info and connect with investors.
Claim profile

Private Company

Total funding raised: $261.5M

Overview

Synthego is a pioneering biotechnology company that has established itself as a key enabler in the CRISPR and molecular diagnostics sectors. By focusing on the engineering and scalable manufacturing of high-performance reagents like synthetic gRNA, nucleases (e.g., SpCas9, hfCas12Max), and diagnostic enzymes, it serves both academic/industrial research and clinical development pipelines. The company supports cell and gene therapy advancement through its GMP manufacturing capabilities and IND submission support, while also addressing the growing demand for rapid, reliable molecular diagnostics with its lyophilized, point-of-care-ready reagents. Synthego operates as a critical infrastructure provider, bridging the gap between discovery and clinical application.

CRISPRGenetics & Genomics

Technology Platform

Engineering and scalable manufacturing platform for synthetic biology components, including synthetic guide RNA (gRNA), engineered CRISPR nucleases (e.g., SpCas9, hfCas12Max), base editors (e.g., AccuBase CBE), and molecular diagnostics reagents (e.g., lyophilized isothermal amplification kits, PCR enzymes).

Funding History

5
Total raised:$261.5M
Series D$100M
Series C$110M
Series B$41M
Series A$9M

Opportunities

Synthego is positioned to capitalize on the rapid growth of the cell and gene therapy market by providing essential GMP-grade CRISPR components and IND support services.
Additionally, the expanding demand for rapid, point-of-care molecular diagnostics creates a significant opportunity for its lyophilized, ambient-stable reagent platform.

Risk Factors

Key risks include intense competition from larger, established life science reagent companies and other CRISPR tool providers, dependence on the clinical success and regulatory acceptance of CRISPR-based therapies, and the challenges of scaling as a private company in a capital-intensive industry.

Competitive Landscape

Synthego competes in the CRISPR research tools market against companies like Integrated DNA Technologies (IDT), Thermo Fisher Scientific, and Horizon Discovery. In GMP manufacturing for therapies, it faces competition from CDMOs like Lonza and Catalent. In molecular diagnostics reagents, it challenges giants such as New England Biolabs, Qiagen, and Thermo Fisher.