Supernus Pharmaceuticals

Supernus Pharmaceuticals

SUPN
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SUPN · Stock Price

USD 52.28+20.58 (+64.92%)
Market Cap: $3.0B

Historical price data

Market Cap: $3.0BPipeline: 75 drugs (25 Phase 3)Patents: 20Founded: 2005HQ: Rockville, United States

Overview

Supernus Pharmaceuticals is a publicly traded CNS-focused biopharmaceutical company with a mission to improve patient lives through innovative neurology and psychiatry treatments. The company has successfully built a commercial foundation with eight marketed products and is advancing a pipeline featuring late-stage candidates for treatment-resistant depression and severe epilepsy. Its strategy combines internal R&D powered by proprietary drug delivery platforms with strategic acquisitions, such as Sage Therapeutics, to solidify its position as a comprehensive CNS therapeutics leader.

NeurologyPsychiatry

Technology Platform

Proprietary drug delivery technology platform designed to optimize pharmacokinetics, improve tolerability, and enable convenient dosing for CNS therapies.

Pipeline

75
75 drugs in pipeline25 in Phase 3
DrugIndicationStageWatch
ZULRESSO®Postpartum DepressionApproved
APOKYNParkinson's DiseaseApproved
SPN-812Attention-Deficit/Hyperactivity Disorder (ADHD)Approved
SPN-812Attention-Deficit/Hyperactivity DisorderApproved
100mg SPN-812 + PlaceboAttention-Deficit/Hyperactivity DisorderApproved

Funding History

1
Total raised:$60M
IPO$60M

FDA Approved Drugs

6
ONAPGONDAFeb 3, 2025
QELBREENDAApr 2, 2021
GOCOVRINDAAug 24, 2017

Opportunities

The acquisition of Sage Therapeutics opens the large, high-need mood disorders market, with SPN-820 representing a major near-term catalyst in treatment-resistant depression.
Continued growth of Qelbree in the expansive ADHD market and successful development of SPN-817 for severe epilepsy offer additional avenues for significant value creation.

Risk Factors

Key risks include commercial execution challenges for recent launches in competitive markets, clinical failure of late-stage pipeline assets SPN-820 and SPN-817, and integration complexities following the transformative Sage Therapeutics acquisition.

Competitive Landscape

Supernus competes with large pharma and specialized biotechs in neurology and psychiatry. Its differentiation stems from proprietary drug delivery technology, a diversified commercial portfolio, and commercial agility. Key competitors include Jazz Pharmaceuticals, UCB, Neurocrine Biosciences, Takeda, and major depression-focused companies.

Company Timeline

2005Founded

Founded in Rockville, United States

2012IPO

IPO — $60.0M

2017FDA Approval

FDA Approval: GOCOVRI

2021FDA Approval

FDA Approval: QELBREE

2025FDA Approval

FDA Approval: ONAPGO