Shionogi

Shionogi

4507.T
Osaka, Japan· Est.
Is this your company? Claim your profile to update info and connect with investors.
Claim profile

4507.T · Stock Price

JPY 3,177+772 (+32.07%)
Market Cap: $17.3B

Historical price data

Market Cap: $17.3BPipeline: 143 drugs (38 Phase 3)Patents: 20Founded: 1878HQ: Osaka, Japan

Overview

Shionogi is a premier, discovery-based Japanese pharmaceutical company with a 65+ year legacy in antibiotic innovation and a mission to supply the best possible medicine to protect patient health. The company has successfully diversified its pipeline beyond its core infectious disease expertise into antivirals, CNS disorders, and rare diseases, while maintaining a steadfast commitment to combating antimicrobial resistance (AMR). Its strategy combines deep in-house R&D capabilities with strategic global partnerships and licensing to accelerate development and commercialize novel therapeutics for serious unmet medical needs worldwide.

Infectious DiseasesCentral Nervous System (CNS)Rare DiseasesVirologyOncology

Technology Platform

Deep expertise in small-molecule drug discovery and development, with specialized platforms in anti-infective medicinal chemistry, virology, and strategic use of AI/digital health partnerships.

Pipeline

143
143 drugs in pipeline38 in Phase 3
DrugIndicationStageWatch
Naldemedine + PlaceboOpioid-Induced Constipation (OIC)Approved
Rosuvastatin + HMG CoA inhibitorHypercholesteremiaApproved
StatinIschemic StrokeApproved
CefiderocolCystic FibrosisApproved
Duloxetine + Pregabalin + PlaceboDiabetic Peripheral Neuropathic PainApproved

FDA Approved Drugs

3
FETROJANDANov 14, 2019
MULPLETANDAJul 31, 2018
METHYLINNDADec 19, 2002

Opportunities

Significant opportunities exist in the growing global markets for novel antibiotics (driven by AMR), oral COVID-19 antivirals, and long-acting HIV therapies.
Expansion into high-value rare and CNS diseases offers potential for premium-priced, specialty products with favorable development pathways.

Risk Factors

Key risks include clinical failure of late-stage pipeline assets, the persistent commercial challenge of marketing novel antibiotics, intense competition in newer therapeutic areas, and dependency on partners for a portion of revenue.
Regulatory and pricing pressures in key markets like the U.S.
also pose ongoing threats.

Competitive Landscape

Shionogi competes as a focused innovator against large pharma in infectious diseases (e.g., Pfizer, Merck in COVID-19; Gilead in HIV) and a shrinking cohort in antibiotics. Its competitive edge lies in deep, sustained expertise in complex anti-infective R&D and a strategic partnership model that expands its reach without overextending resources.

Company Timeline

1878Founded

Founded in Osaka, Japan

2002FDA Approval

FDA Approval: METHYLIN

2018FDA Approval

FDA Approval: MULPLETA

2019FDA Approval

FDA Approval: FETROJA