Semler Scientific

Semler Scientific is a US-based medical technology company focused on the early detection and management of chronic diseases, primarily through its flagship QuantaFlo® system for diagnosing Peripheral Arterial Disease (PAD). The company has achieved significant milestones, including FDA clearance, HITRUST certifications, and recognition on the Deloitte Technology Fast 500 and Forbes Top 100 Small-Cap lists. Its strategy centers on leveraging its installed hardware base to drive recurring revenue through test kits and expanding its software-as-a-service (SaaS) offerings, including data analytics and secure cloud platforms, to create a comprehensive digital health ecosystem.

Centered on the QuantaFlo® system, a point-of-care vascular plethysmography device for PAD detection, integrated with a HITRUST-certified cloud ecosystem (SemlerHub, Analytics, Vault, Shield) for data management, security, and actionable insights.

Semler competes with traditional Ankle-Brachial Index (ABI) testing, other point-of-care vascular devices, and large medtech imaging conglomerates. Its key advantages are its focused FDA clearance for finger/toe testing, established reimbursement, integrated HITRUST-certified data platform, and first-mover installed base in the asymptomatic screening niche.