RefleXion Medical

RefleXion Medical is pioneering a transformative approach to radiation therapy with its proprietary Scintix biology-guided radiotherapy system. This technology leverages PET signals from injected radiotracers to detect and continuously track tumors, allowing for automated, high-precision radiation delivery that can adapt to tumor motion and treat multiple metastatic sites simultaneously. Founded in 2009 and based in Hayward, California, the company represents a significant convergence of radiotherapy, diagnostic imaging, and radiopharmaceuticals. Its platform has the potential to shift radiation oncology from a primarily anatomic-based, pre-planned modality to a real-time, biology-driven treatment, particularly for patients with metastatic disease.

Biology-Guided Radiotherapy (BgRT) - A platform integrating real-time PET imaging with a linear accelerator to dynamically target and treat tumors based on their biological signal, enabling treatment of multiple and moving lesions.

RefleXion competes directly with major radiotherapy equipment manufacturers like Varian (Siemens Healthineers) and Elekta, who offer advanced SBRT and MRI-guided systems. It also faces competition from specialized platforms like Accuray's CyberKnife for stereotactic treatment. Its unique BgRT approach differentiates it, but it must displace entrenched technologies and workflows.