Presidio Medical

Presidio Medical

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Private Company

Total funding raised: $105M

Overview

Presidio Medical is a private, clinical-stage medical device company pioneering a new approach to neuromodulation for chronic nociceptive pain. Its core technology, the Ultra Low Frequency (ULF™) Neuromodulation System, is designed to inhibit neuronal activity at the pain site, offering a potential therapeutic option for a large patient population underserved by current neuropathic pain-focused devices. Led by a seasoned management team with deep experience from companies like Boston Scientific, Abbott, and Alcon, the company is positioned to address a significant unmet need in the chronic pain market. Presidio is currently in the development and clinical validation stage, building its team and advancing its technology toward commercialization.

Chronic PainNociceptive Pain

Technology Platform

Ultra Low Frequency (ULF™) Neuromodulation System designed to inhibit neuronal responses for treating chronic nociceptive pain and other diseases of undesired neural activity.

Funding History

2
Total raised:$105M
Series B$75M
Series A$30M

Opportunities

Presidio targets a large, underserved patient population with chronic nociceptive pain, a condition historically overlooked by existing neuromodulation devices focused on neuropathic pain.
Success could establish a new therapeutic category within the multi-billion dollar neuromodulation market, with potential for expansion into other diseases of undesired neural activity.

Risk Factors

Key risks include the clinical failure of its novel ULF technology, significant regulatory hurdles for a Class III implantable device, and the future challenge of commercializing a new therapy in a competitive pain management landscape.
The company is also dependent on raising substantial additional capital to fund development through to potential approval.

Competitive Landscape

Presidio competes in the broad neuromodulation market dominated by large players like Medtronic, Boston Scientific, and Abbott, but its specific focus on nociceptive pain creates a differentiated niche. Its primary competition comes from existing pain management options (e.g., opioids, NSAIDs, injections, physical therapy) and other device-based therapies not optimized for nociceptive mechanisms.