Outpace Bio

Outpace Bio

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Private Company

Total funding raised: $186.5M

Overview

Outpace Bio is a private, pre-clinical stage biotech pioneering AI-driven protein design to develop next-generation cell therapies for solid tumors. The company's platform creates novel, fully human protein functions to address multiple failure points in current treatments, including immunosuppressive tumor microenvironments, poor T-cell persistence, and lack of specificity. By integrating its modular technology suite (OUTSMART™, OUTLAST™, OUTSPACER™, OUTSAFE™, and logic gating) into cell therapies, Outpace aims to build curative products for a broad range of cancers that are currently untreatable with existing cell therapy approaches.

Oncology

Technology Platform

AI-powered protein design platform that creates novel, fully human protein functions to program cell therapies. The modular platform includes technologies for optimized CAR spacing (OUTSPACER™), designed cytokines (OUTSMART™), T-cell persistence (OUTLAST™), safety switches (OUTSAFE™), and logic-gated targeting.

Funding History

3
Total raised:$186.5M
Series B$144M
Series A$30M
Seed$12.5M

Opportunities

The solid tumor cell therapy market represents a vast, unmet need encompassing >95% of cancer cases.
Outpace's modular platform could enable curative therapies for these indications and position the company as a key technology provider for the next generation of cell therapies across multiple therapeutic areas.

Risk Factors

High technical risk associated with the novel approach of using de novo designed proteins to control complex human biology in vivo.
Significant competition in the next-generation cell therapy space and dependence on future fundraising in a challenging financial environment for early-stage biotechs.

Competitive Landscape

Outpace operates in the highly competitive field of next-generation cell therapy for solid tumors, competing with companies developing armored CAR-Ts, cytokine engineering, logic gates, and synthetic biology platforms. Key differentiators are its focus on fully human, AI-designed novel protein functions (beyond natural protein engineering) and its integrated, modular approach to solving multiple barriers simultaneously.