NinthBio

NinthBio is a private, early-stage biotech tools company founded in 2018, offering a software-driven platform for cost-effective, in-house DNA library synthesis. Its Homology Path technology uses an aggressive oligo recycling algorithm to design DNA assembly from a minimal set of oligos, reportedly saving customers up to 90% in costs and reducing turnaround from weeks to days. The company operates a SaaS-like business model with tiered access plans, targeting DNA service providers and protein engineering labs seeking to internalize and accelerate their variant generation workflows.

Homology Path: A proprietary bioinformatics software platform that designs DNA variant libraries for synthesis by identifying shared sequence scaffolds to minimize the number of required oligonucleotides, enabling cost-effective, in-house PCR assembly.

NinthBio competes indirectly with large DNA synthesis service providers (e.g., Twist Bioscience, GenScript, IDT) by offering a tool to bypass their library synthesis services. Direct competitors could include other bioinformatics software companies offering DNA library design tools. Its key differentiation is a specific, aggressive focus on oligo recycling for variant libraries, promising superior cost savings.