Neurelis

Neurelis

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Private Company

Total funding raised: $150M

Overview

Neurelis is a private, commercial-stage biopharmaceutical company specializing in neurology, with a core focus on epilepsy. The company has built its portfolio around proprietary drug delivery enhancement technologies—Intravail®, ProTek®, and Hydrogel™—which enable non-invasive administration of therapeutics. Its lead commercial product is Valtoco® (diazepam nasal spray) for acute treatment of seizure clusters, and it maintains a pipeline of investigational neurology candidates. Neurelis operates with a patient-centric model, offering savings and support programs to ensure access to its therapies.

EpilepsyNeurology

Technology Platform

Proprietary drug delivery and stabilization technologies including Intravail® (transmucosal absorption enhancer), ProTek® (stabilization), and Hydrogel™ (controlled release), designed for non-invasive delivery of peptides, proteins, and small molecules.

Funding History

2
Total raised:$150M
Debt$100M
Series D$50M

Opportunities

Significant opportunity to expand the market for acute seizure rescue therapies through increased diagnosis and patient awareness, moving patients from older, less convenient options.
The proprietary drug delivery platform presents a major opportunity for out-licensing or co-development with partners for applications in neurology and beyond, creating additional revenue streams.

Risk Factors

Faces intense competition in the acute seizure market from other approved nasal sprays and delivery devices.
As a private, commercial-stage company, it carries execution risk in driving product sales growth and pipeline development while managing cash flow.
Regulatory or clinical setbacks for pipeline candidates could limit long-term growth.

Competitive Landscape

In acute seizure treatment, Neurelis's Valtoco® competes directly with UCB's Nayzilam® (midazolam nasal spray) and Bausch Health's Diastat® (diazepam rectal gel). The competitive landscape emphasizes convenience, reliability, and speed of administration. The company's technology platform also positions it against other drug delivery specialty firms, competing on the basis of enhancement efficacy and breadth of molecule applicability.