Myricx Bio

Myricx Bio

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Private Company

Total funding raised: $207.7M

Overview

Myricx Bio is a private, preclinical-stage biotechnology company pioneering a first-in-class approach to antibody-drug conjugates (ADCs) by utilizing N-myristoyltransferase (NMT) inhibitors as cytotoxic payloads. Founded in 2020 and headquartered in London with a US presence in Boston, the company is backed by a strong syndicate of life science investors including Abingworth, Brandon Capital, and Novo Holdings. Under new CEO Mohit Rawat, who brings significant ADC and transaction expertise from Fusion Pharmaceuticals, Myricx is advancing its platform, which has shown compelling preclinical efficacy and safety across multiple solid tumor models.

Oncology

Technology Platform

Proprietary platform for developing N-myristoyltransferase (NMT) inhibitors as novel cytotoxic payloads for Antibody-Drug Conjugates (ADCs).

Funding History

3
Total raised:$207.7M
Series A$114M
Series A$90M
Seed$3.7M

Opportunities

The rapidly expanding ADC market, valued in the tens of billions, presents a major opportunity for a novel payload class that could overcome resistance and toxicity issues of existing therapies.
The platform's applicability across multiple tumor targets allows for a broad pipeline and potential for lucrative partnerships or platform licensing deals with large pharma.

Risk Factors

High scientific risk as the NMT inhibitor ADC approach is unproven in humans.
The company faces intense competition in the ADC space and is dependent on future financing to advance its costly preclinical programs into clinical trials.

Competitive Landscape

Myricx competes in the crowded and innovative ADC payload space, facing companies developing novel warheads like immunostimulants, protein degraders, and other enzyme inhibitors. Its differentiation hinges on the first-in-class NMT inhibition mechanism. It also competes for funding and partnership attention with other preclinical/platform biotechs.