MoonLake Immunotherapeutics

MoonLake Immunotherapeutics

MLTXPhase 3
Zug, SwitzerlandFounded 2021moonlaketx.com

MoonLake Immunotherapeutics is a Swiss biotech focused on developing next-generation immunotherapies using its proprietary Nanobody® technology platform. The company's lead asset, sonelokimab, is a first-in-class trivalent Nanobody® targeting IL-17A and IL-17F, with a promising clinical profile in inflammatory skin and joint diseases. Following a successful merger and public listing, MoonLake is advancing sonelokimab into late-stage development, aiming to establish a new standard of care in hidradenitis suppurativa and expand into other autoimmune indications.

Market Cap
$1.2B
Founded
2021
Employees
50-100
Focus
Biotech

MLTX · Stock Price

USD 16.27+6.38 (+64.51%)

Historical price data

AI Company Overview

MoonLake Immunotherapeutics is a Swiss biotech focused on developing next-generation immunotherapies using its proprietary Nanobody® technology platform. The company's lead asset, sonelokimab, is a first-in-class trivalent Nanobody® targeting IL-17A and IL-17F, with a promising clinical profile in inflammatory skin and joint diseases. Following a successful merger and public listing, MoonLake is advancing sonelokimab into late-stage development, aiming to establish a new standard of care in hidradenitis suppurativa and expand into other autoimmune indications.

Technology Platform

Proprietary Nanobody® platform for developing small, stable, multivalent antibody fragments that target inflammatory pathways, enabling potentially superior tissue penetration and target engagement compared to conventional monoclonal antibodies.

Pipeline Snapshot

10

10 drugs in pipeline, 7 in Phase 3

DrugIndicationStage
Sonelokimab + Placebo + RisankizumabArthritis, PsoriaticPhase 3
SonelokimabHidradenitis SuppurativaPhase 3
SonelokimabHidradenitis SuppurativaPhase 3
Sonelokimab + PlaceboHidradenitis SuppurativaPhase 3
SonelokimabArthritis, PsoriaticPhase 3

Funding History

2

Total raised: $60M

IPOUndisclosedUndisclosedMar 24, 2022
Series A$60MForbionMar 15, 2021

Opportunities

Significant market opportunity in hidradenitis suppurativa, a disease with high unmet need and limited treatment options.
Expansion into the large psoriatic arthritis market and potential application of the Nanobody® platform to other inflammatory diseases provide long-term growth avenues.

Risk Factors

High dependency on the success of a single clinical asset, sonelokimab.
Faces intense competition from large, established pharmaceutical companies in immunology.
Requires successful Phase 3 trial outcomes and regulatory approvals to generate revenue.

Competitive Landscape

Competes against major pharma companies like AbbVie, Novartis, Johnson & Johnson, and UCB in dermatology and rheumatology. Key differentiation is sonelokimab's trivalent Nanobody® structure targeting both IL-17A and IL-17F, aiming for best-in-class efficacy in hidradenitis suppurativa and psoriatic arthritis.

Publications
5
Pipeline
10

Company Info

TypeTherapeutics
Founded2021
Employees50-100
LocationZug, Switzerland
StagePhase 3
RevenuePre-revenue

Trading

TickerMLTX
ExchangeNASDAQ

Therapeutic Areas

DermatologyRheumatologyImmunology

Partners

Ablynx/Sanofi (Nanobody® platform license)
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