Minerva Neurosciences

Minerva Neurosciences

NERV
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NERV · Stock Price

USD 6.13-1.41 (-18.77%)
Market Cap: $281.9M

Historical price data

Market Cap: $281.9MPipeline: 6 drugs (1 Phase 3)Founded: 2007Employees: 11-50HQ: Waltham, United States

Overview

Minerva Neurosciences is a publicly traded, clinical-stage biotech company focused on addressing significant unmet medical needs in central nervous system disorders, particularly schizophrenia and Parkinson's disease. Founded in 2007, the company's core strategy centers on its specialized expertise in clinical trial design, aiming to demonstrate clear patient benefit through carefully selected endpoints and patient populations. While currently pre-revenue, its value proposition lies in its ability to potentially de-risk late-stage development in challenging CNS indications. The company faces the critical challenge of advancing its pipeline through clinical milestones with limited financial resources.

SchizophreniaParkinson's Disease

Technology Platform

Clinical development expertise focused on designing innovative trials with patient-centric endpoints and strategic patient selection to de-risk development in central nervous system disorders.

Pipeline

6
6 drugs in pipeline1 in Phase 3
DrugIndicationStageWatch
Placebo Oral Tablet + Roluperidone 32 mg + Roluperidone 64 m...Negative Symptoms of SchizophreniaPhase 3
MIN-117 5.0 mg + MIN-117 2.5 mg + PlaceboMajor Depressive DisorderPhase 2
MIN-101Healthy SubjectsPhase 1
MIN-101Healthy SubjectsPhase 1
MIN-101 + PlaceboSchizophreniaPhase 1

Funding History

4
Total raised:$135M
PIPE$40M
IPO$60M
Series B$25M
Series A$10M

Opportunities

Potential to address massive unmet needs with no approved therapies: negative symptoms of schizophrenia and Parkinson's disease psychosis.
Success with roluperidone could establish a first-in-class franchise.
Specialized clinical trial design expertise may de-risk development and create partnership value.

Risk Factors

Lead asset roluperidone received a Complete Response Letter from the FDA, creating a major regulatory and clinical hurdle.
Company is pre-revenue with limited cash runway, posing significant financial and dilution risk.
Pipeline is highly concentrated, with value heavily dependent on a single asset facing development challenges.

Competitive Landscape

Faces competition from large pharma and biotechs in both schizophrenia and Parkinson's disease psychosis. In negative symptoms, it races against other late-stage programs for first approval. In Parkinson's psychosis, it must compete against an established, approved therapy (pimavanserin) and other novel agents in development.

Company Timeline

2007Founded

Founded in Waltham, United States

2014IPO

IPO — $60.0M

2014Series B

Series B: $25.0M

2018PIPE

PIPE: $40.0M