Makani Science

Makani Science is a private, pre-revenue medical device company focused on reinventing respiratory monitoring. Its core technology is a wearable patch sensor that wirelessly transmits real-time breathing waveforms to mobile platforms, enabling immediate detection of respiratory events. The company targets the growing market for monitoring patients undergoing sedation or opioid therapy, addressing a critical need to prevent respiratory failure. Its leadership includes experienced engineers and a CEO with a background in bringing medical devices to market.

Wearable patch sensor for continuous, wireless, noninvasive monitoring of respiratory rate, relative tidal volume, and minute ventilation. Data is transmitted in real-time to mobile platforms for clinical display.

Makani competes in the broad respiratory monitoring device market against large incumbents like Medtronic, Philips, and Masimo, as well as startups. It must differentiate from standard capnography and pulse oximetry by offering continuous volumetric data (tidal volume) in a wearable form factor, targeting earlier detection of respiratory depression.