Legend Biotech

Legend Biotech

LEGN
Is this your company? Claim your profile to update info and connect with investors.
Claim profile

LEGN · Stock Price

USD 28.57-3.21 (-10.10%)
Market Cap: $5.2B

Historical price data

Market Cap: $5.2BPipeline: 36 drugsFounded: 2014Employees: 1000+HQ: Somerset, United States

Overview

Legend Biotech's mission is to discover, develop, and commercialize transformative cell therapies for patients with life-threatening diseases, primarily in oncology. Its core achievement is the successful global launch of CARVYKTI® (cilta-cel), a best-in-class CAR-T therapy for multiple myeloma, which has propelled the company to commercial leadership and validated its technology platform. The company's strategy centers on deepening its commercial footprint, advancing a broad pipeline of next-generation cell therapies, and expanding its manufacturing capabilities, all underpinned by a strategic global collaboration with Janssen (Johnson & Johnson).

OncologyHematology

Technology Platform

A proprietary, integrated, and technology-agnostic cell therapy platform for developing and manufacturing autologous and allogeneic cellular immunotherapies, including CAR-T, CAR-NK, and TCR-based therapies.

Pipeline

36
36 drugs in pipeline
DrugIndicationStageWatch
LCAR-B38M CAR-T CellMultiple MyelomaPhase 2
LCAR-B38M CAR-T cell injectionRefractory or Relapsed Multiple MyelomaPhase 1/2
LCAR-AIO T cellsMultiple Sclerosis (MS)Phase 1
LCAR-HL30 cellsHodgkin's LymphomaPhase 1
LCAR-AIO CellsAcute Lymphocytic LeukemiaPhase 1

Funding History

2
Total raised:$537M
IPO$487M
Series A$50M

Opportunities

Legend's primary opportunities include expanding CARVYKTI® into earlier lines of multiple myeloma therapy, potentially increasing its addressable patient population by 5-10x, and successfully pioneering CAR-T therapy in large solid tumor markets like small cell lung cancer and gastric cancer, which represent a vastly larger frontier.

Risk Factors

Key risks include clinical failure or safety issues for cilta-cel in earlier-line trials, intense competition in multiple myeloma from other CAR-Ts and bispecific antibodies, the high risk of failure for earlier-stage solid tumor programs, and operational complexities in cell therapy manufacturing and the global supply chain.

Competitive Landscape

Legend competes directly with Bristol Myers Squibb/2seventy bio's Abecma in multiple myeloma, and with major cell therapy players like Gilead/Kite and Novartis in hematologic cancers. Its push into solid tumors and allogeneic therapies places it in a more fragmented but high-potential competitive field against numerous clinical-stage biotechs.

Company Timeline

2014Founded

Founded in Somerset, United States

2018Series A

Series A: $50.0M

2020IPO

IPO — $487.0M