Kura Oncology

Kura Oncology

KURAApproved
San Diego, United StatesFounded 2014kuraoncology.com

Kura Oncology's mission is to realize the promise of precision medicines to help patients with cancer lead better, longer lives. Founded in 2014, the company leverages deep scientific understanding of cancer biology to develop targeted therapies for areas of high unmet need, including head and neck cancer, lung cancer, and acute leukemias. Kura's strategy involves investigating its therapies in combination with standards of care to forge new paths for durable remissions. The company is led by an experienced team and is publicly traded on NASDAQ under the ticker KURA.

Market Cap
$729.6M
Founded
2014
Focus
Small Molecules

KURA · Stock Price

USD 8.267.64 (-48.05%)

Historical price data

AI Company Overview

Kura Oncology's mission is to realize the promise of precision medicines to help patients with cancer lead better, longer lives. Founded in 2014, the company leverages deep scientific understanding of cancer biology to develop targeted therapies for areas of high unmet need, including head and neck cancer, lung cancer, and acute leukemias. Kura's strategy involves investigating its therapies in combination with standards of care to forge new paths for durable remissions. The company is led by an experienced team and is publicly traded on NASDAQ under the ticker KURA.

Technology Platform

Precision oncology platform focused on developing small molecule inhibitors targeting specific oncogenic pathways, with a historical emphasis on the RAS pathway and farnesyltransferase inhibition.

Pipeline Snapshot

21

21 drugs in pipeline, 1 in Phase 3

DrugIndicationStage
Ziftomenib + Placebo + Venetoclax + Azacitidine (AZA) + Daunorubicin + Cytarabin...Acute Myeloid Leukemia (AML)Phase 3
TipifarnibThyroid CancerPhase 2
TipifarnibLeukemia, Myelomonocytic, ChronicPhase 2
Cytarabine + Hydroxyurea + ZiftomenibAcute Myeloid LeukemiaPhase 2
TipifarnibHRAS Gene MutationPhase 2

FDA Approved Drugs

1
KOMZIFTINDANov 13, 2025

Opportunities

Key growth opportunities include successful clinical development and approval of tipifarnib in HRAS-mutant HNSCC, expansion into other biomarker-defined cancer populations, and developing effective combination regimens to improve treatment durability and address resistance.
The precision oncology market continues to expand, offering significant potential for targeted therapies.

Risk Factors

Major risks include clinical trial failures, regulatory setbacks, intense competition in oncology, potential difficulties in raising capital as a pre-revenue company, and reliance on the success of a lead clinical asset (tipifarnib).
The company's valuation is highly sensitive to clinical data readouts.

Competitive Landscape

Kura faces competition from large pharma oncology portfolios and other biotechs in targeted therapy. In HNSCC, competitors include checkpoint inhibitors (Keytruda, Opdivo). In the RAS pathway space, direct KRAS G12C inhibitors (Lumakras, Krazati) are competitors, though targeting different nodes. Kura aims to differentiate by focusing on specific subsets like HRAS-mutant cancers and combination approaches.

Publications
19
Patents
20
Pipeline
21
FDA Approvals
1

Company Info

TypeTherapeutics
Founded2014
LocationSan Diego, United States
StageApproved
RevenuePre-revenue

Trading

TickerKURA
ExchangeNASDAQ

Therapeutic Areas

OncologyHead and Neck CancerLung CancerAcute Leukemias

Partners

Janssen Pharmaceutica NV (tipifarnib in-licensing)
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