Ischemia Care

Ischemia Care

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Private Company

Funding information not available

Overview

Ischemia Care is a private, commercial-stage diagnostics company founded in 2017 and headquartered in San Francisco, CA. It has pioneered a blood-based RNA expression test (ISCDx) to determine the cause of ischemic stroke, addressing the significant clinical challenge of cryptogenic (unknown cause) strokes. The company's platform is supported by data from the large, prospective BASE clinical trial (NCT02014896), which enrolled 1,700 patients. Ischemia Care aims to integrate its testing into clinical workflows to enable precision secondary stroke prevention and reduce healthcare costs.

NeurologyCardiology

Technology Platform

Blood-based diagnostic platform using RNA expression analysis (transcriptomics) and artificial intelligence to determine stroke etiology and related conditions.

Opportunities

The large addressable market of ~250,000 annual cryptogenic strokes in the U.S.
presents a direct opportunity for ISCDx adoption.
Expanding the platform into emergency room triage and ambulatory settings could significantly increase the company's market reach and impact on stroke care pathways.

Risk Factors

Key risks include the challenge of driving clinical adoption and securing insurance reimbursement for a novel diagnostic test.
The company also faces competitive risks from other entities developing stroke biomarkers and regulatory uncertainty as the LDT landscape evolves.

Competitive Landscape

Ischemia Care positions itself as the first and only company with a commercially available RNA-based test for stroke etiology. Competition exists from companies researching protein biomarkers (e.g., Banyan Biomarkers' CTE blood test had a stroke indication) and extensive academic research into multi-omics biomarkers for stroke, but no direct, widely adopted commercial competitor is currently evident in the stroke etiology sub-field.