Immix Biopharma

Immix Biopharma

IMMX
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IMMX · Stock Price

USD 9.54+7.45 (+356.46%)
Market Cap: $500.2M

Historical price data

Market Cap: $500.2MPipeline: 2 drugsPatents: 5Founded: 2012Employees: 11-50HQ: Los Angeles, United States

Overview

Immix Biopharma's mission is to harness the immune system through innovative cell therapies to deliver widely accessible cures. The company's core achievement is the development of its N-GENIUS platform, which has produced NXC-201, a CAR-T therapy demonstrating a transformative safety profile with 0% neurotoxicity in AL amyloidosis and high response rates. Its strategy is to overcome the primary barrier to CAR-T adoption—neurotoxicity—to expand into new disease indications and the 95% of U.S. medical centers currently unable to dose existing CAR-T therapies, starting with a planned BLA submission in AL amyloidosis.

OncologyHematology

Technology Platform

N-GENIUS Sterically-Optimized Cell Therapy Platform with EXPAND technology, engineered to dramatically reduce neurotoxicity and cytokine release syndrome while maintaining therapeutic efficacy in CAR-T therapies.

Pipeline

2
2 drugs in pipeline
DrugIndicationStageWatch
Imx-110Solid Tumor, AdultPhase 1/2
NXC-201 CAR-TLight Chain (AL) AmyloidosisPhase 1/2

Funding History

3
Total raised:$30M
IPO$15M
Series A$12M
Seed$3M

Opportunities

NXC-201 has the potential to be the first approved CAR-T therapy for relapsed/refractory AL amyloidosis, an orphan disease with high unmet need.
Its superior safety profile could enable expansion into the 95% of U.S.
hospitals currently unable to administer CAR-Ts and allow penetration into earlier lines of therapy in larger markets like multiple myeloma.

Risk Factors

Key risks include the failure of the pivotal NEXICART-2 trial to confirm earlier efficacy/safety data, regulatory delays post-BLA submission, challenges in commercializing a first-in-class therapy for a rare disease, and intense competition in the multiple myeloma space from next-generation therapies.

Competitive Landscape

In AL amyloidosis, NXC-201 is a first-mover CAR-T with no direct cell therapy competitors. In multiple myeloma, it faces established, highly efficacious CAR-Ts (Abecma, Carvykti) but differentiates on a potentially best-in-class safety profile, aiming to enable broader, earlier-line use rather than competing on headline efficacy in late-line patients.

Company Timeline

2012Founded

Founded in Los Angeles, United States

2018Seed

Seed: $3.0M

2020Series A

Series A: $12.0M

2021IPO

IPO — $15.0M