Geron
GERNGERN · Stock Price
Historical price data
Overview
Geron Corporation is a commercial-stage biopharmaceutical company with a mission to extend and enhance the lives of patients with blood cancers by changing the course of disease through targeted telomerase inhibition. The company achieved a historic milestone with the June 2024 FDA approval of its first-in-class telomerase inhibitor, imetelstat (Rytelo™), for transfusion-dependent anemia in lower-risk myelodysplastic syndromes (MDS). Geron's strategy is to leverage its proprietary platform to expand imetelstat's label into other myeloid malignancies, including myelofibrosis (MF) and acute myeloid leukemia (AML), aiming to build a leading franchise in hematologic oncology.
Technology Platform
Proprietary platform focused on telomerase inhibition, leveraging Nobel Prize-winning science to develop oligonucleotide inhibitors that target the enzyme enabling unlimited replication in cancer cells, particularly in hematologic malignancies.
Pipeline
21| Drug | Indication | Stage | Watch |
|---|---|---|---|
| Imetelstat + Best Available Therapy (BAT) | Myelofibrosis | Phase 3 | |
| Imetelstat Sodium + Placebo | Myelodysplastic Syndromes | Phase 2/3 | |
| Imetelstat (7.5 mg/kg) + lenalidomide standard of care + Ime... | Multiple Myeloma | Phase 2 | |
| Imetelstat | Primary Myelofibrosis | Phase 2 | |
| Imetelstat sodium + Bevacizumab + Paclitaxel | Locally Recurrent or Metastatic Breast Cancer | Phase 2 |
Funding History
3FDA Approved Drugs
1Company Timeline
Founded in Foster City, United States
IPO — $27.0M
PIPE: $100.0M
PIPE: $150.0M
FDA Approval: RYTELO