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Endovascular Engineering

Endovascular Engineering

San Francisco, United States· Est.
endovascularengineering.com
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Private Company

Total funding raised: $1.8M

Overview

Endovascular Engineering is a private, clinical-stage medical device company developing the Hēlo™ Thrombectomy System for pulmonary embolism. The company has completed a feasibility study and is currently running a pivotal FDA IDE trial (ENGULF) to support a 510(k) clearance. Backed by $42M in Series B financing and led by an experienced team, E2 aims to address a significant unmet need in the large and growing VTE market with a differentiated, purpose-built device.

CardiovascularVenous Thromboembolism

Technology Platform

The Hēlo™ Thrombectomy System platform features a small-profile catheter with a self-expanding distal funnel for large-bore clot engagement and dual-action technology combining high-speed mechanical agitation with simultaneous aspiration for clot breakdown and removal.

Funding History

1
Total raised:$1.8M
Seed$1.8M

Opportunities

The large and growing global VTE market, driven by an aging population and improved diagnostics, presents a significant opportunity.
The shift toward interventional therapies for PE and the need for purpose-built, safer thrombectomy devices create a clear entry point for the Hēlo system's differentiated technology.

Risk Factors

The company faces significant clinical and regulatory risk, as its value is contingent on the success of its single pivotal trial.
It also faces intense competition from larger, established medical device companies and must successfully execute a commercial launch in a crowded market with a novel technology.

Competitive Landscape

The PE thrombectomy market is competitive, featuring devices from large medtech players (e.g., Boston Scientific, Philips, Inari Medical) and specialized startups. Many current devices are adapted from other indications, whereas Endovascular Engineering's Hēlo system is purpose-built for PE, aiming to differentiate on profile, safety, and single-pass efficacy.

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