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Electra Therapeutics

Electra Therapeutics

South San Francisco, United States· Est.
electra-therapeutics.com
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Private Company

Total funding raised: $183M

Overview

Electra Therapeutics is a private, clinical-stage biotech focused on developing novel SIRP-targeted antibodies with a unique mechanism of action for immunology and oncology. The company's lead asset, ELA026, is advancing in a pivotal Phase 2/3 trial for the life-threatening hyperinflammatory disease sHLH, with expansion into hematologic cancers planned. A second program, ELA822, is being advanced toward the clinic for immunology and inflammation. With a presentation scheduled at a major healthcare conference, the company is actively seeking visibility as it progresses its pipeline.

ImmunologyOncology

Technology Platform

Platform for discovering and developing antibodies targeting Signal Regulatory Protein (SIRP) with a claimed unique mechanism of action.

Funding History

1
Total raised:$183M
Series C$183M

Opportunities

ELA026 addresses a life-threatening condition (sHLH) with no approved therapies, enabling potential for high pricing and rapid adoption.
The SIRP platform offers expansion into large markets like hematologic cancers and broad autoimmune diseases, providing multiple shots on goal for value creation.

Risk Factors

Clinical failure of the lead candidate ELA026 in its pivotal Phase 2/3 trial is an existential risk.
The novel SIRP mechanism may harbor unforeseen safety issues.
The company is pre-revenue and dependent on external financing in a challenging capital market.

Competitive Landscape

The CD47-SIRP axis is competitive, with multiple companies developing blockers for oncology. Electra must differentiate its 'unique mechanism' against these and other myeloid-targeting therapies. In sHLH, it may compete with generic immunosuppressants and targeted agents like emapalumab.

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