Day One Biopharmaceuticals
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Overview
Day One Biopharmaceuticals is a mission-driven oncology company founded to address the systemic failure of traditional drug development to deliver timely therapies for children with cancer. The company's innovative 'Search & Development' model focuses on acquiring and developing promising clinical-stage or approved targeted therapies for high-unmet-need cancers. A major milestone was achieved in 2024 with the FDA approval of OJEMDA™ for pediatric low-grade glioma, transitioning Day One into a commercial entity and proving its unique operational strategy. The company is now leveraging this success to expand its pipeline through strategic acquisitions and internal development.
Technology Platform
A 'Search & Development' operational model focused on proactively identifying, acquiring, and developing clinical-stage or approved targeted therapies for high-unmet-need cancers through a network-driven approach.
Pipeline
8| Drug | Indication | Stage | Watch |
|---|---|---|---|
| Tovorafenib + Chemotherapeutic Agent | Low-grade Glioma | Phase 3 | |
| Tovorafenib | Low-grade Glioma | Phase 2 | |
| Tovorafenib | Craniopharyngioma, Child | Phase 2 | |
| Tovorafenib | Melanoma | Phase 2 | |
| DAY301 | Advanced or Metastatic Solid Tumors | Phase 1 |
FDA Approved Drugs
2Company Timeline
Founded in Brisbane, United States
FDA Approval: OJEMDA
FDA Approval: OJEMDA