Cutiss

Cutiss

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Private Company

Total funding raised: $65M

Overview

CUTISS is a pioneering Swiss biotech company developing denovoSkin™, a personalized, bioengineered skin graft intended to replace the current standard of autografting. The company operates a state-of-the-art GMP facility and has developed a proprietary, automated manufacturing platform for scalable production. With denovoSkin™ in late-stage clinical trials and holding Orphan Drug Designations from major regulatory bodies, CUTISS is positioned to address significant unmet needs in burn care, reconstructive surgery, and beyond, while also exploring applications in regenerative medicine and space health research.

BurnsReconstructive SurgeryDermatology

Technology Platform

Proprietary, automated, closed-system platform for scalable bio-manufacturing of personalized tissue grafts (denovoSkin™). Also holds license for Viticell®, a cell therapy device for skin pigmentation restoration.

Funding History

2
Total raised:$65M
Series B$50M
Series A$15M

Opportunities

The global skin surgery market is large and growing.
denovoSkin™ addresses the significant limitations of autografting, offering a superior clinical and economic profile.
The scalable automation platform allows for expansion into other regenerative medicine tissues (gums, cornea) and non-healthcare applications, creating multiple long-term growth vectors.

Risk Factors

Key risks include clinical/regulatory failure in ongoing late-stage trials, challenges in securing reimbursement for a high-cost advanced therapy, and operational complexities in scaling up novel, automated manufacturing of living tissue.
Competition from other regenerative medicine approaches also poses a threat.

Competitive Landscape

CUTISS is first-in-class with a personalized, bioengineered skin graft. It competes against the entrenched standard of care (autografting) and a range of wound care products, skin substitutes, and scaffolds that support or augment autografting. Its fully integrated, automated production platform for a living bilayer skin graft is a key differentiator from other tissue engineering approaches.