CorInnova

CorInnova

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Private Company

Total funding raised: $2.5M

Overview

CorInnova is pioneering a disruptive approach to mechanical circulatory support with its minimally invasive, non-blood contacting cardiac assist device. Backed by a lead investment from the Wellcome Trust, the company targets the acute heart failure market, seeking to treat patients unsuitable for existing blood-contacting devices. Its technology promises to eliminate risks like thrombosis and stroke, potentially expanding the addressable market to $5 billion. CorInnova is in the preclinical/development stage, building a strong advisory board and securing non-dilutive grant funding.

CardiovascularHeart Failure

Technology Platform

Minimally invasive, implantable cardiac assist system for Direct Cardiac Compression (DCC). The device is collapsible, non-blood contacting, and uses external pneumatic actuation to synchronously compress the heart, increasing cardiac output without the risks of thrombosis or need for anticoagulants.

Funding History

2
Total raised:$2.5M
Seed$2M
Grant$500K

Opportunities

The primary opportunity is to capture a large portion of the estimated $5B market by treating acute heart failure patients who are contraindicated for existing blood-contacting assist devices, potentially representing 50% of the patient population.
Successful clinical validation could also open pathways for longer-term applications and establish a new device category in mechanical circulatory support.

Risk Factors

Key risks include the failure of the novel device to demonstrate safety and efficacy in upcoming human trials, potential surgical complications from a new implantation technique, and the challenge of achieving adoption in a crowded market dominated by established players.
Securing sufficient funding to complete costly clinical development is also a significant risk.

Competitive Landscape

CorInnova competes in the acute mechanical circulatory support market against established devices like Abiomed's Impella, Getinge/MAQUET's IABP and Cardiohelp system, and Abbott's CentriMag. Its primary competitive advantage is the non-blood contacting design, which aims to avoid the major complications (bleeding, thrombosis, stroke) associated with these incumbent technologies, targeting patients currently without a viable device option.