ClostraBio

ClostraBio

ClostraBio is focused on restoring intestinal barrier-protective function and innate immunity to maintain gut health and treat diseases of the gut and food allergy. The company leverages a well-rounded team of scientists and entrepreneurs with expertise in microbiology and bioengineering to develop both a dietary supplement and a versatile delivery platform. Their core technology aims to transform intestinal health through targeted metabolite delivery, addressing significant unmet needs in the IBD and food allergy markets.

Private Company

Total funding raised: $16M

AI Company Overview

ClostraBio is focused on restoring intestinal barrier-protective function and innate immunity to maintain gut health and treat diseases of the gut and food allergy. The company leverages a well-rounded team of scientists and entrepreneurs with expertise in microbiology and bioengineering to develop both a dietary supplement and a versatile delivery platform. Their core technology aims to transform intestinal health through targeted metabolite delivery, addressing significant unmet needs in the IBD and food allergy markets.

GastroenterologyImmunologyAllergy

Technology Platform

A plug-and-play platform for the targeted delivery of bacterial metabolites to the gut, designed to restore intestinal barrier function and modulate innate immunity for treating gastrointestinal and allergic diseases.

Funding History

2
Total raised:$16M
Series A$12M
Seed$4M

Opportunities

The primary growth opportunities lie in successfully validating the metabolite delivery platform, which could generate multiple therapeutic candidates for large markets like IBD and food allergy.
Additionally, the near-term commercial launch of CLB101™ as a dietary supplement could provide non-dilutive revenue and brand recognition.

Risk Factors

Key risks include the unproven clinical efficacy of metabolite-based therapeutics, navigating complex regulatory pathways for novel modalities, and intense competition from well-established pharmaceutical companies and other microbiome-focused biotechs.

Competitive Landscape

ClostraBio faces competition from large pharma in IBD (AbbVie, J&J) and food allergy (Nestlé/Aimmune), as well as other microbiome biotechs (Vedanta, Seres). Its differentiation is the focus on targeted delivery of specific metabolites, rather than live bacteria, aiming for precise modulation of gut physiology.