ClostraBio

ClostraBio

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Private Company

Total funding raised: $16M

Overview

ClostraBio is focused on restoring intestinal barrier-protective function and innate immunity to maintain gut health and treat diseases of the gut and food allergy. The company leverages a well-rounded team of scientists and entrepreneurs with expertise in microbiology and bioengineering to develop both a dietary supplement and a versatile delivery platform. Their core technology aims to transform intestinal health through targeted metabolite delivery, addressing significant unmet needs in the IBD and food allergy markets.

GastroenterologyImmunologyAllergy

Technology Platform

A plug-and-play platform for the targeted delivery of bacterial metabolites to the gut, designed to restore intestinal barrier function and modulate innate immunity for treating gastrointestinal and allergic diseases.

Funding History

2
Total raised:$16M
Series A$12M
Seed$4M

Opportunities

The primary growth opportunities lie in successfully validating the metabolite delivery platform, which could generate multiple therapeutic candidates for large markets like IBD and food allergy.
Additionally, the near-term commercial launch of CLB101™ as a dietary supplement could provide non-dilutive revenue and brand recognition.

Risk Factors

Key risks include the unproven clinical efficacy of metabolite-based therapeutics, navigating complex regulatory pathways for novel modalities, and intense competition from well-established pharmaceutical companies and other microbiome-focused biotechs.

Competitive Landscape

ClostraBio faces competition from large pharma in IBD (AbbVie, J&J) and food allergy (Nestlé/Aimmune), as well as other microbiome biotechs (Vedanta, Seres). Its differentiation is the focus on targeted delivery of specific metabolites, rather than live bacteria, aiming for precise modulation of gut physiology.