Claret Bioscience

Claret Bioscience is a private, platform technology company providing innovative NGS library preparation solutions for degraded and low-input nucleic acid samples. Its flagship SRSLY® technology is a single-reaction, single-stranded DNA library prep kit that preserves native fragment ends, enabling superior analysis of cfDNA for liquid biopsy research, forensics, and ancient DNA studies. The company has secured non-dilutive funding through an SBIR grant and a key automation partnership, positioning it in the high-growth genomics tools market with a focus on research use and potential quality control applications in biomanufacturing.

SRSLY® (Single Reaction Single-stranded DNA Library Prep) platform: A ligation-based NGS library preparation technology that preserves native DNA ends and works with single-stranded inputs, enabling analysis of degraded DNA (cfDNA, FFPE, ancient DNA) and RNA. Includes Forshear™ fragmentation and REALLY™ RNA-Seq modules.

Claret competes in the NGS library prep market against giants like Illumina, Thermo Fisher Scientific, and Qiagen, as well as specialists like NuGen, Diagenode, and Swift Biosciences. Its differentiation hinges on superior performance with degraded samples and end-preservation, but it must overcome the market dominance, brand recognition, and broad portfolios of its larger competitors.