ChromaCode

ChromaCode

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Private Company

Total funding raised: $48M

Overview

ChromaCode is a private diagnostics company commercializing its High-Definition PCR (HDPCR™) technology, a platform that significantly expands the multiplexing capability of standard digital PCR. By using amplitude modulation and spectral encoding of standard TaqMan probes paired with its ChromaCode Cloud analytics software, the company aims to provide NGS-level genomic content with the speed, simplicity, and lower cost of PCR. Its initial focus is on oncology applications, including tumor profiling and minimal residual disease (MRD) testing, targeting a large market opportunity by enabling labs to increase throughput and margins. The company appears to be in an early revenue stage, leveraging a reagent kit and software-as-a-service business model.

Oncology

Technology Platform

High-Definition PCR (HDPCR™) platform combining proprietary chemistry (using amplitude modulation and multi-spectral encoding of standard TaqMan probes) with the ChromaCode Cloud, a cloud-based data analysis and decoding software. The instrument-agnostic platform enables extreme multiplexing (>4x conventional dPCR) on standard PCR instruments.

Funding History

2
Total raised:$48M
Series B$30M
Series A$18M

Opportunities

Large and growing addressable markets in tumor profiling, MRD, and transplant rejection monitoring, where labs seek NGS-comparable content with PCR simplicity and cost.
The capital-light, high-margin business model (reagents + SaaS) is attractive for scaling and partner adoption.

Risk Factors

Intense competition from both established PCR players and evolving NGS platforms.
Navigating complex regulatory and reimbursement pathways for clinical diagnostics.
Execution risk in commercial scaling and technology adoption by labs.

Competitive Landscape

Competes with low-plex PCR assay providers (e.g., Bio-Rad, Qiagen, Thermo Fisher) by offering higher multiplexing, and with NGS companies (e.g., Illumina, Guardant Health) by offering a simpler, faster, lower-cost alternative for specific applications. Also competes with other advanced dPCR and multiplexing technologies.