CERo Therapeutics

CERo Therapeutics

Pre-clinical
South San Francisco, United StatesFounded 2018cero.bio

CERo Therapeutics is developing next-generation cell therapies designed to overcome limitations of current immunotherapies by creating multifunctional T cells. Its proprietary CER platform engineers T cells to recognize 'Eat Me' signals on tumors, enabling them to engulf cancer cells, kill them directly, and present tumor antigens to stimulate a broader, secondary immune response. This integrated approach aims to enhance curative potential and safety, positioning CERo in the competitive but high-potential field of advanced cell therapies for oncology.

Founded
2018
Focus
Cell & Gene Therapy

AI Company Overview

CERo Therapeutics is developing next-generation cell therapies designed to overcome limitations of current immunotherapies by creating multifunctional T cells. Its proprietary CER platform engineers T cells to recognize 'Eat Me' signals on tumors, enabling them to engulf cancer cells, kill them directly, and present tumor antigens to stimulate a broader, secondary immune response. This integrated approach aims to enhance curative potential and safety, positioning CERo in the competitive but high-potential field of advanced cell therapies for oncology.

Technology Platform

The Chimeric Engulfment Receptor (CER) platform engineers autologous T cells to integrate innate immune functions (phagocytosis, antigen presentation) with adaptive immune T-cell killing, creating multifunctional cells designed to attack cancer through multiple mechanisms.

Funding History

1

Total raised: $77M

Series A$77MMubadala CapitalJan 15, 2022

Opportunities

The primary opportunity lies in successfully developing a cell therapy that works for both blood cancers and the vastly larger solid tumor market.
The platform's potential to stimulate a broad, endogenous immune response could also open doors in combination therapies and cancer vaccines.

Risk Factors

Major risks include the preclinical stage of development, the high technical complexity of manufacturing multifunctional cells, potential for novel safety issues, and intense competition from well-funded companies in the cell therapy space.

Competitive Landscape

Competes with established CAR-T leaders in hematology and a crowded field of next-gen cell therapy developers targeting solid tumors. Key differentiation is the integration of phagocytic 'eating' capability and antigen presentation into a therapeutic T cell, a hybrid approach not yet commercialized.

Company Info

TypeTherapeutics
Founded2018
LocationSouth San Francisco, United States
StagePre-clinical
RevenuePre-revenue

Contact

Therapeutic Areas

Oncology
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