Biopico Systems

Biopico Systems Inc. is a leader in developing interacting multiple organ systems, or microphysiological systems (MPS), aiming to revolutionize in vitro biomedical research. Its flagship OrganRX™ system is described as the world's first unidirectional gravity-driven flow multiorgan system in a multiwell plate format, enabling the study of cross-organ communication, systemic toxicity, and disease pathology. The company targets the critical need for more predictive preclinical models in drug development, particularly for complex biologics, by offering a platform that balances operational simplicity with physiological complexity. Biopico engages with partners through custom model development, compound profiling, and drug development collaborations.

The OrganRX™ platform is a gravity-driven, multiwell plate-based microphysiological system (MPS) that uses Laplace fluidic-stop channels and programmable tilting to create unidirectional recirculation, enabling co-culture of tissues in 3D gels without artificial membranes for modeling human multiorgan physiology.

Biopico competes in the organ-on-a-chip/MPS market against companies like Emulate, Mimetas, and CN Bio. Its main differentiation is its gravity-driven flow system for operational simplicity and its focus on multiorgan communication within a familiar multiwell plate format, combined with an integrated service offering for drug developers.