BeOne Medicines

BeOne Medicines

ONC
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ONC · Stock Price

USD 317.00+81.06 (+34.36%)
Market Cap: $32.9B

Historical price data

Overview

BeOne Medicines is a global, publicly traded oncology company with a mission to deliver transformative cancer treatments through scientific excellence and rapid execution. The company has established itself with two commercial-stage assets, BRUKINSA and TEVIMBRA, and a deep, multi-modality pipeline targeting high-burden blood cancers, solid tumors, and rare malignancies. Its strategy leverages a global clinical and commercial footprint, significant R&D investment, and a multi-platform technology approach to capture substantial market opportunities in oncology.

OncologyHematology

Technology Platform

A multi-modality platform encompassing targeted therapies (BTK, BCL2 inhibition) and novel modalities like the Chimeric Degradation Activation Compound (CDAC) platform for targeted protein degradation.

Pipeline

84
84 drugs in pipeline18 in Phase 3
DrugIndicationStageWatch
ZanubrutinibWaldenström's MacroglobulinemiaApproved
Tislelizumab + Pamiparib + Temozolomide + Sitravatinib + Oci...Advanced MalignanciesPhase 3
Zanidatamab + Tislelizumab + Trastuzumab + Capecitabine + Ox...Gastric NeoplasmsPhase 3
Zanubrutinib + Bendamustine + Rituximab + VenetoclaxChronic Lymphocytic LeukemiaPhase 3
Tislelizumab + Placebo + Cisplatin + Gemcitabine Hydrochlori...Urothelial CarcinomaPhase 3

Funding History

3
Total raised:$175M
IPOUndisclosed
Series B$125M
Series A$50M

FDA Approved Drugs

3
BRUKINSANDAJun 10, 2025
TEVIMBRABLAMar 13, 2024
BRUKINSANDANov 14, 2019

Opportunities

BeOne is positioned to capture significant market share in the multi-billion-dollar BTK inhibitor and immuno-oncology markets through its approved products.
Its late-stage BCL2 inhibitor and novel CDAC protein degradation platform offer substantial upside potential in next-generation hematology treatments and novel cancer biology.

Risk Factors

Key risks include clinical failure of pivotal pipeline assets, intense competition in core markets from established pharmaceutical giants, operational complexity of managing a global organization, and geopolitical and market access challenges across numerous countries.

Competitive Landscape

BeOne faces fierce competition in its core areas: against AbbVie, AstraZeneca, and others in BTK inhibition; against Merck and Bristol Myers Squibb in PD-1 inhibition; and against a host of biotechs and large pharma in novel modalities like protein degradation. Its integrated global model is a key differentiator.