Arima Genomics

Arima Genomics

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Private Company

Total funding raised: $23M

Overview

Arima Genomics, founded in 2015 and based in San Diego, is a leader in 3D genomics, commercializing a robust Hi-C technology platform. The company operates a dual business model, providing research tools and services while also offering a CLIA-certified clinical diagnostic test (Aventa) for detecting gene fusions and rearrangements in cancer. With a recent $22 million Series C financing and partnerships with companies like Velsera, Arima is positioned to expand the adoption of its structural genomics approach in both research and clinical markets.

Oncology

Technology Platform

Proprietary Hi-C (High-throughput Chromosome Conformation Capture) technology, a proximity ligation method that captures the 3D organizational structure of chromatin to provide integrated sequence and structural genomic data.

Funding History

2
Total raised:$23M
Series A$20M
Seed$3M

Opportunities

The growing need in precision oncology to detect complex structural variants like gene fusions creates a major opportunity for Arima's Aventa test.
Additionally, the expanding research fields of 3D genomics and high-quality genome assembly provide substantial markets for its platform products and services.

Risk Factors

Key risks include slower-than-expected adoption of 3D genomics in clinical and research settings, challenges in securing insurance reimbursement for its clinical test, and competition from larger, established genomic companies offering alternative technologies.

Competitive Landscape

Arima competes with other 3D genomics specialists (e.g., Dovetail Genomics, now part of Cantata Bio), large NGS companies like Illumina and PacBio for structural variant analysis, and numerous clinical diagnostic labs offering NGS-based oncology panels. Its differentiation lies in the comprehensiveness of its Hi-C-based structural detection.