Aligos Therapeutics

Aligos Therapeutics

ALGS
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ALGS · Stock Price

USD 6.03-0.78 (-11.45%)
Market Cap: $39.6M

Historical price data

Market Cap: $39.6MFounded: 2018Employees: 50-100HQ: South San Francisco, United States

Overview

Aligos Therapeutics is a clinical-stage biotech focused on developing best-in-class therapies for chronic liver and viral diseases, specifically chronic hepatitis B (CHB) and MASH. The company employs a targeted, chemistry-driven approach to design small molecules with optimized pharmacological profiles. Its strategy centers on a lean, experienced team with a proven track record in hepatology and virology drug development, aiming to advance a focused pipeline through key clinical milestones. Despite a challenging financial position with a low market valuation, its progress is defined by upcoming Phase 2 data for its lead assets.

HepatologyVirology

Technology Platform

A chemistry-driven approach leveraging deep expertise in medicinal chemistry and disease biology to design optimized small molecule drugs for viral and liver diseases, without a single proprietary technological platform.

Funding History

3
Total raised:$275M
PIPE$80M
IPO$150M
Series A$45M

Opportunities

Positive Phase 2 data for Pevifoscorvir could position it as a cornerstone for finite-duration HBV combination therapies targeting a functional cure.
Success for ALG-055009 in MASH could capture a share of a multi-billion dollar market, potentially as a differentiated second-generation THR-β agonist.

Risk Factors

The company faces high clinical trial risk with its concentrated pipeline, significant financial risk due to its pre-revenue status and low market cap, and intense competition in both the CHB and MASH therapeutic landscapes.

Competitive Landscape

In CHB, Pevifoscorvir competes with other capsid assembly modulators, siRNA, and antisense therapies in pursuit of a curative regimen. In MASH, ALG-055009 enters a validated but competitive field against the approved Resmetirom and other late-stage THR-β agonists and novel mechanisms.

Company Timeline

2018Founded

Founded in South San Francisco, United States

2018Series A

Series A: $45.0M

2020IPO

IPO — $150.0M

2021PIPE

PIPE: $80.0M